The MOUSE ANTI HUMAN TALIN-1 Antibody from MyBioSource.com is a Mouse Monoclonal antibody to Talin, Talin 1, and TLN1. This antibody recognizes Human antigen. The MOUSE ANTI HUMAN TALIN-1 Antibody has been validated for the following applications: Immunofluorescence, Immunohistochemistry, Immunoprecipitation, and Western Blot.
Description
Mouse anti Human Talin-1 antibody, clone 97H6 recognizes an epitope within the region of amino acids 482-655 of humanTalin-1, a high molecular weight cytoskeletal protein, linking vinculin to the integrins, thereby linking the cytoskeleton to the extracellular matrix. It is specifically found in regions of cell-substratum contact and in lymphocytes at cell-cell contact points. Talin-1 plays a role in the assembly of actin filaments and in the migration of cells such as osteoclasts and fibroblasts